name='stuart.scot']As I understand it Cary Grant was the first choice to play James Bond, but turned it down because he didn't want to do more than one film.
Some fans might have had difficulty in seeing him play a Goverment assassin. However, I think Roger Moore and Cary Grant had a similar acting style, so If he had have played Bond I think he would have been terrific. However, he would have been 61 at the time of Dr. No, so I can't imagine him going beyond Goldfinger. But if he had accepted the role, we might never have heard of Sean Connery.
IMO as well Errol Flynn would have made a splendid Bond, either as a young man or as a fit healthy 53 yr old at the time Dr. No was made. Sadly as we all know Flynn self destructed and was dead at 50 after yrs of abusive hell raising.